Related Experiment Video
Updated: Jun 19, 2026

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits (Oryctolagus cuniculus)
Published on: July 31, 2021
EPIDEMIOLOGICAL STUDIES ON RESPIRATORY INFECTIONS OF THE RABBIT : VI. ETIOLOGY OF OTITIS MEDIA
1Laboratories of The Rockefeller Institute for Medical Research.
Abstract:
A common form of otitis media occurring in rabbits is described. The condition in the great majority of instances is associated with the inflammation of the upper respiratory tract known as snuffles and with the presence of Bacterium lepisepticum. This organism, when introduced into the external nares of rabbits hitherto protected from infection with it, is capable of inducing a purulent otitis media indistinguishable from the natural one. In the rabbit the connection between the nasal passages and the middle ear is such that a pathogenic agent introduced into the nose may readily invade the entire group of cavities connected with the upper respiratory tract.
Related Concept Videos
Respiratory Syncytial Virus Disease
Microbiota of the Respiratory Tract
