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Updated: Jun 19, 2026
Epithelial Cell Infection Analyses with Shigella
Published on: February 9, 2024
STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE
E Perlman1, F Binkley, W F Goebel
1Laboratories of The Rockefeller Institute for Medical Research.
Abstract:
1. Volunteers have been immunized with the purified specific antigen of Type V Shigella paradysenteriae (Flexner). The subjects developed a high titer of bacterial agglutinins and mouse-protective antibodies. The agglutinin titer fell moderately after a period of 6 months. The subjects responded fairly well to a small recall dose of the antigen. 2. Two individuals from a group of 10 injected with the specific polysaccharide obtained from Type V organisms responded with an increase in bacterial agglutinins. Mouse-protective antibodies were demonstrable in the one serum tested.
