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Immunohistochemistry in Kaposi's sarcoma

L Pantanowitz1, C N Otis, B J Dezube

  • 1Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, MA, USA. liron.pantanowitz@bhs.org

Clinical and Experimental Dermatology
|October 31, 2009
PubMed

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Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
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