Related Experiment Video
Updated: Jun 19, 2026
12:23
Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Uveodermatologic syndrome in an Akita.
1Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.
The Canadian Veterinary Journal = La Revue Veterinaire Canadienne
|November 3, 2009
Summary
A Japanese Akita experienced sudden blindness and eye issues, diagnosed as uveodermatologic syndrome. Treatment with prednisone and azathioprine successfully restored the dog's vision.
Area of Science:
- Veterinary Ophthalmology
- Immunology
Background:
- Uveodermatologic syndrome is an immune-mediated condition affecting the eyes and skin.
- Early diagnosis and treatment are crucial for managing ocular inflammatory diseases in dogs.
Observation:
- An 8-year-old female Japanese Akita presented with acute blindness, cloudy eyes, and squinting.
- Clinical signs suggested a diagnosis of uveodermatologic syndrome.
Findings:
- A treatment regimen including oral prednisone, topical prednisolone, and oral azathioprine was initiated.
- The therapy led to the resolution of most clinical signs associated with the syndrome.
Implications:
- This case highlights the efficacy of a multi-modal treatment approach for canine uveodermatologic syndrome.
- Prompt intervention can result in complete vision restoration in affected dogs, improving their quality of life.
Related Concept Videos
01:23Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
01:27Adrenal Gland Disorders
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...