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Published on: January 25, 2016
Report on hearing loss in oncology
Christiane Schultz1, Maria Valéria Schmidt Goffi-Gomez, Patrícia Helena Pecora Liberman
1Audiology Sector, Hospital do Câncer A C Camargo.
Brazilian Journal of Otorhinolaryngology
|November 7, 2009
Summary
Current hearing loss criteria are inadequate for identifying cisplatin-induced ototoxicity in cancer patients. Further research is needed to improve patient quality of life by better understanding chemotherapy-related hearing loss.
Area of Science:
- Oncology
- Audiology
- Pharmacology
Background:
- Cisplatin is a vital antineoplastic drug for various cancers.
- High-dose cisplatin (over 360mg/m²) can cause ototoxicity, leading to hearing loss.
- Standardized criteria for identifying and quantifying chemotherapy-induced hearing loss are crucial.
Purpose of the Study:
- To evaluate the effectiveness of different hearing loss classification systems in oncologic patients.
- To determine the implications of these classification systems for managing cisplatin-induced ototoxicity.
- To assess the sensitivity and specificity of various criteria in identifying hearing loss post-chemotherapy.
Main Methods:
- Hearing loss was assessed in 31 cancer patients before and after chemotherapy.
- Multiple classification systems were applied to quantify hearing loss.
- Sensitivity and specificity of each system were analyzed.
Main Results:
- Hearing loss prevalence varied significantly (29%-61%) across different criteria.
- Only 4 out of 31 patients with hearing loss were consistently identified by all methods.
- Some patients with hearing loss were misclassified as having normal hearing by certain criteria.
- A normal pure-tone average (PTA) was observed in 18 out of 31 patients post-treatment.
Conclusions:
- Existing hearing loss criteria failed to adequately identify patients experiencing chemotherapy-induced ototoxicity.
- The current classification systems do not incorporate patient-reported symptoms or complaints.
- Improved criteria are necessary for physicians to accurately assess hearing loss and its impact on patients' quality of life.
Related Concept Videos
Hearing
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
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In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
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