Related Experiment Video
Updated: Jun 18, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
Published on: September 22, 2023
[The study of correlation between allergen and chronic rhinosinusitis]
1Department of Otolaryngology, Second Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Objective:
To explore the effects of allergic factors in chronic sinusitis.
Method:
Skin prick test and specific serum IgE of 194 patients with chronic sinusitis were performed in our department before endoscopic sinus surgery from October, 2007 to October, 2008, and correlation between test results and clinical classification was analyzed retrospectively.
Result:
(1) Result of skin prick test was analyzed. Positive rate of house dust was 20. 6% (40/194), of dust mites 16.0% (30/194), of house dust mites 14.9% (29/194). (2) Positive rate of allergic specific serum IgE and skin prick test in experimental group was compared with that of control group. Positive rate of house dust mites, dust mites and house dust between groups were significantly different (P < 0.05). (3) Clinical classification of chronic sinusitis had a negative correlation with the specific serum IgE (house dust mites ,house dust and dust mites) about experimental group (P < 0.05).
Conclusion:
Allergic factors was associated with etiopathogenesis and course of disease of chronic sinusitis.
Related Concept Videos
Asthma I: Introduction
Allergic Reactions
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-I: Introduction
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
