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Updated: Jun 18, 2026
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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
[Palliative surgery for locally advanced prostate cancer]
Orit Raz1, Louis L Pisters, Phillip E Spiess
1Assaf-Harofeh Medical Center, Zerifin Israel, Sackler Faculty of Medicine, Tel Aviv University.
Harefuah
|November 11, 2009
Summary
Locally advanced prostate cancer (LAPC) involves tumor growth beyond the prostate, causing significant symptoms and reduced quality of life. Effective palliation is crucial for managing LAPC, even if a cure is not possible.
Area of Science:
- Oncology
- Urology
Context:
- Locally advanced prostate cancer (LAPC) is defined by tumor extension beyond the prostatic capsule.
- This progression invades adjacent pelvic structures like the bladder, rectum, and ureters.
Purpose:
- To describe the clinical syndrome of locally advanced prostate cancer (LAPC).
- To outline current treatment options for effective palliation in LAPC patients.
Summary:
- LAPC causes significant morbidity, including urinary obstruction, renal failure, hematuria, and pelvic pain.
- Despite potential for long-term survival (over 5 years) in some non-metastatic cases, cure is often not achievable.
- Effective palliation is a critical clinical endpoint to improve quality of life.
Impact:
- Highlights the importance of palliative care in managing LAPC symptoms.
- Informs clinicians and patients about the challenges and goals of LAPC treatment.
