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Updated: Jun 18, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
Published on: February 23, 2024
Activity of antioxidant enzymes in the wound in patients with deep burns
E V Mikhal'chik1, J A Piterskaya, V A Lipatova
1Russian State Medical University, Moscow, Russia. lemik2007@yandex.ru
Abstract:
Analysis of wound discharge in children with deep burns over 3 weeks after the injury revealed gradual increase in catalase activity. The increase in activities of myeloperoxidase, glutathione-S-transferase, and catalase was maximum in patients with the most severe burns. Local complications were observed during the period of maximum myeloperoxidase activity, while the beginning of epithelialization was associated with its reduction. Analysis of wound impressions confirms long-term persistence of neutrophils in the wound.
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