Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Two-Dimensional (2D) NMR: Overview

Two-Dimensional (2D) NMR: Overview

The 1D NMR spectrum of large and complex molecules like natural products has complicated splitting patterns and overlapping signals, which can be easily interpreted using 2-dimensional (2D) NMR. Unlike 1D NMR, 2D NMR has two frequency axes that provide the coupling information between the nucleus A and nucleus B in a molecule. The process from which 2D spectra are obtained has four steps.
The first step is the preparation period, during which nucleus A is excited with a radiofrequency pulse.

Molecular Models

Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.

Network Covalent Solids

Network Covalent Solids

Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...

¹H NMR: Interpreting Distorted and Overlapping Signals

¹H NMR: Interpreting Distorted and Overlapping Signals

Spin systems where the difference in chemical shifts of the coupled nuclei is greater than ten times J are called first-order spin systems. These nuclei are weakly coupled, and their chemical shifts and coupling constant can generally be estimated from the well-separated signals in the spectrum.
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are slanted or...

Molecular Orbital Theory II

Molecular Orbital Theory II

Molecular Orbital Energy Diagrams

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Redirecting On-surface Cycloaddition Reactions in a Self-assembled Ordered Molecular Array on Graphite.

Angewandte Chemie (International ed. in English)·2025

Same author

Is Semiconducting Transition-Metal Dichalcogenide Suitable for Spin Pumping?

Nano letters·2024

Same author

Electro-Optical Multiclassification Platform for Minimizing Occasional Inaccuracy in Point-of-Care Biomarker Detection.

Advanced materials (Deerfield Beach, Fla.)·2024

Same author

Epitaxial Growth of 2D Binary Phosphides.

Small methods·2024

Same author

Tunable Spin-Polarized States in Graphene on a Ferrimagnetic Oxide Insulator.

Advanced materials (Deerfield Beach, Fla.)·2023

Same author

Ultra-Fast Single-Nucleotide-Variation Detection Enabled by Argonaute-Mediated Transistor Platform.

Advanced materials (Deerfield Beach, Fla.)·2023

Same journal

Large-Area Atomically Flat Monocrystalline Gold Flakes: Recent Advances, Applications, and Future Potential.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

Decoupling Processing-Morphology-Stability Relationships Enables 19.65% Organic Solar Cells With Exceptional Photostability.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

Tunable and Selective Doping Modulation in Pd-Filled Carbon Nanotube Transistors.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

Multifunctional Microgels: From Material Design to Skin Wound Healing Applications.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

A Tissue-Homologous Keratin-PBA Hydrogel Integrating Rationally Designed Nanomicelles Enables Microenvironment-Adaptive Repair of Chronic Diabetic Wounds.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

Modulation of 1D Ru-Porphyrin Biomimetic COF to Enhance Synergistic Dual C─H Bond Air Oxidation for Cyclohexenone Synthesis.

Small (Weinheim an der Bergstrasse, Germany)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 18, 2026

Tuning the Contractility and Deformation Modes of Active Actin-Based Assemblies In Vitro: From Two-Dimensional Active Networks to Liquid Crystal Drops

Tuning the Contractility and Deformation Modes of Active Actin-Based Assemblies In Vitro: From Two-Dimensional Active Networks to Liquid Crystal Drops

Published on: July 11, 2025

Tunable two-dimensional binary molecular networks.

Yu Li Huang¹, Wei Chen, Hui Li

¹Department of Physics National University of Singapore 2 Science Drive 3, 117542 Singapore. phycw@nus.edu.sg

Small (Weinheim an Der Bergstrasse, Germany)

|November 11, 2009

Summary

This summary is machine-generated.

Researchers developed a new method to create tunable and stable 2D molecular nanostructures on graphite. This technique uses hydrogen bonds to control molecular arrangements for advanced electronic and sensing applications.

More Related Videos

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

Related Experiment Videos

Last Updated: Jun 18, 2026

Tuning the Contractility and Deformation Modes of Active Actin-Based Assemblies In Vitro: From Two-Dimensional Active Networks to Liquid Crystal Drops

Tuning the Contractility and Deformation Modes of Active Actin-Based Assemblies In Vitro: From Two-Dimensional Active Networks to Liquid Crystal Drops

Published on: July 11, 2025

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

Area of Science:

Surface science
Supramolecular chemistry
Nanotechnology

Background:

Fabricating ordered molecular nanostructures on surfaces is challenging.
Controlling intermolecular interactions is key for creating functional nanomaterials.

Purpose of the Study:

To present a novel method for constructing tunable and robust 2D binary molecular nanostructures.
To explore the use of intermolecular hydrogen bonds for molecular assembly.

Main Methods:

Embedding guest molecules within a host molecular matrix on a graphite surface.
Utilizing multiple intermolecular hydrogen bonds for molecular constraint.
Varying binary molecular ratios and geometries to tune nanostructure formation.

Main Results:

Successfully fabricated tunable 2D binary molecular nanostructures.
Achieved control over intermolecular distances through molecular ratio and geometry.
Demonstrated the robustness and stability of the constructed nanostructures.

Conclusions:

The presented approach offers a promising route for fabricating ordered and stable molecular nanostructure arrays.
These nanostructures have potential applications in molecular sensors, spintronic devices, and nanojunctions.