Related Experiment Video
Updated: Jun 18, 2026
06:34
Laser-Induced Chronic Ocular Hypertension Model on SD Rats
Published on: December 4, 2007
Long-Term Intraocular Pressure Control After Nd-YAG Laser Iridotomy in Chronic Angle-Closure Glaucoma.
1Department of Ophthalmology, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa.
Journal of Glaucoma
|November 19, 2009
Summary
Nd-YAG laser iridotomy is effective for chronic angle-closure glaucoma management. Careful follow-up is crucial for patients with advanced disease to monitor intraocular pressure and visual fields.
Area of Science:
- Ophthalmology
- Glaucoma Research
Background:
- Chronic angle-closure glaucoma (CACG) poses a significant risk to vision.
- Nd-YAG laser iridotomy is a common intervention for this condition.
Purpose of the Study:
- To evaluate the long-term efficacy of Nd-YAG laser iridotomy in managing CACG.
- To assess the need for subsequent medical therapy or surgery.
Main Methods:
- Retrospective study of 52 patients (78 eyes) with CACG undergoing Nd-YAG laser iridotomy.
- Mean follow-up of 22 months, analyzing intraocular pressure (IOP) and treatment requirements.
Main Results:
- 51.3% of eyes achieved IOP <22 mm Hg with medication; 9% without.
- 29.5% of eyes eventually required trabeculectomy.
- Predictive factors for trabeculectomy included high presenting IOP, extensive angle closure, and high cup:disc ratio, but prediction accuracy was limited.
Conclusions:
- Nd-YAG laser iridotomy, followed by medical therapy and/or trabeculectomy, is an effective strategy for CACG.
- Close monitoring of IOP and visual fields is essential, particularly in advanced cases.
Related Concept Videos
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...