Related Experiment Video
Updated: Jun 18, 2026

Generation of Null Mutants to Elucidate the Role of Bacterial Glycosyltransferases in Bacterial Motility
Published on: March 11, 2022
Glycosyltransferase functions of E. coli O-antigens
Magnus Lundborg1, Vijayachitra Modhukur, Göran Widmalm
1Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden.
Abstract:
ECODAB (the E. coli O-antigen database) has been expanded to include information about glycosyltransferases (GTs) involved in the assembly of the O-antigen polysaccharide. Similarity searches have been performed to be able to determine GT functions that have not been reported prior to this work. In addition to suggesting the function of 179 GTs, the approach leads to the prediction of part of the O-antigen structures of a number of serogroups. The procedure suggests a novel way of combining genetic information with experimental techniques in structural analysis of oligo- and polysaccharides.
Related Concept Videos
Oligosaccharide Assembly
Multiple sugar molecules that may or may...
Protein Glycosylation
Glycosylation occurs in...
Proteoglycans
Glycocalyx and its Functions
Components of...
Bacterial Gastroenteritis
Protein Folding Quality Check in the RER
