Related Experiment Video
Updated: Jun 18, 2026

Freezing, Thawing, and Packaging Cells for Transport
Published on: July 2, 2008
[The fragile beginning of the vaccine cold chain in Spain]
1Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de Ciencia, Universidad de Alicante, Alicante, España. tuells@ua.es
Abstract:
Two studies aiming to analyze the vaccine cold chain throughout Spain, performed from 1988-89, sparked interest in vaccine logistics among public health authorities. The studies were performed using evaluation methodology based on cold chain monitor cards with a time-temperature indicator (Battersby's report) and cross-sectional surveys on the conditions of the cold chain (Ferrando's report) in the second and third levels (provincial and local stores). The technical reports revealed the precariousness of the situation, identified the weak points that were jeopardizing the vaccines' efficiency, and favored awareness of an activity that constitutes the vertebral column of any immunization program. The improvements proposed were gradually implemented by regional governments. More funds for equipment and personnel training were provided and specific management protocols were established.
Related Concept Videos
Vaccine Production
Pasteurization and Food Preservation
Vaccines
Vaccinations
Principles of Food Preservation
Sample Handling
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...

