Calreticulin: non-endoplasmic reticulum functions in physiology and disease

Leslie I Gold1, Paul Eggleton, Mariya T Sweetwyne

  • 1Departments of Medicine and Pathology, New York, University School of Medicine, 550 First Ave., NB16S13 New York, NY 10016 USA. leslie.gold@nyumc.org

Summary

Calreticulin (CRT) functions beyond the endoplasmic reticulum (ER), impacting cell adhesion, migration, and immune responses. Extracellular CRT also enhances wound healing, revealing its broader physiological roles.

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