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Updated: Jun 18, 2026
03:41
High-Resolution Ultrasonography for the Analysis of Orthotopic ATC Tumors in a Genetically Engineered Mouse Model
Published on: October 11, 2022
[A giant thoracoabdominal tumor--hereditary multiple exostoses].
C Nistor1, A Ciuche, M Davidescu
1Clinica de Chirurgie Toracică, Spitalul Clinic de Urgenţă Militar Central Bucureşti, România.
Chirurgia (Bucharest, Romania : 1990)
|December 1, 2009
Summary
Hereditary multiple exostoses (HME) can cause large tumors. This case details the successful surgical removal of a 2.6 kg osteochondroma from a teenager, restoring function and aesthetics.
Area of Science:
- Orthopedics
- Genetics
- Surgical Oncology
Background:
- Hereditary multiple exostoses (HME), or osteochondromatosis, is an autosomal dominant disorder characterized by skeletal osteochondromas.
- Patients often require multiple orthopedic interventions for limb deformities.
Observation:
- A 17-year-old male with a history of HME presented with a giant osteochondroma (2.6 kg) at the thoraco-abdominal border.
- The tumor involved the ribs, thoracic wall, abdominal wall, and retroperitoneal space.
Findings:
- The patient underwent successful total tumor resection, including thoracic and abdominal parietectomy.
- Reconstruction involved a dual-mesh soft tissue patch and diaphragm reinsertion, preserving function and aesthetics.
Implications:
- This case highlights the feasibility of radical surgical management for massive HME-associated tumors.
- Successful surgical outcomes can be achieved with meticulous surgical planning and reconstruction, improving patient quality of life.
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