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Updated: Jun 18, 2026

A Novel Method: Super-selective Adrenal Venous Sampling

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Published on: September 15, 2017

Symptomatic hypocalcemia in primary hyperaldosteronism: a case report.

Sachin G Pai¹, K N Shivashankara, V Pandit

¹Department of Medicine, Kasturba Medical College, Manipal, Karnataka, India. sachingpai@gmail.com

Journal of Korean Medical Science

|December 2, 2009

Summary

This summary is machine-generated.

Primary hyperaldosteronism can cause severe metabolic disturbances, including symptomatic hypocalcemia and weight loss, alongside hypertension. Surgical treatment of the adrenal adenoma resolved these complex symptoms.

Keywords:

Hypocalcemia Primary Aldosteronism Weight Loss

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Last Updated: Jun 18, 2026

A Novel Method: Super-selective Adrenal Venous Sampling

A Novel Method: Super-selective Adrenal Venous Sampling

Published on: September 15, 2017

Area of Science:

Endocrinology
Nephrology
Metabolic Medicine

Background:

Primary hyperaldosteronism is increasingly linked to metabolic changes, particularly in congestive cardiac failure.
Its impact on calcium and parathyroid metabolism remains less understood.
Recent research explores novel mechanisms behind these metabolic alterations.

Observation:

A case of primary hyperaldosteronism due to adrenal adenoma (Conn's syndrome) presented with severe symptoms.
Clinical features included symptomatic hypocalcemia, significant weight loss, and prolonged, uncontrolled hypertension.
These symptoms persisted before the underlying condition was diagnosed.

Findings:

Surgical resection of the adrenal adenoma was performed.
Post-surgery, all clinical symptoms and signs rapidly resolved.
The patient regained lost weight, indicating a direct link between the adenoma and the metabolic derangements.

Implications:

This case highlights the critical, yet often overlooked, effects of primary hyperaldosteronism on calcium and overall metabolism.
It underscores the importance of considering hyperaldosteronism in patients with unexplained hypocalcemia, weight loss, and hypertension.
Successful surgical intervention demonstrates the curable nature of Conn's syndrome and its associated metabolic complications.