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Related Experiment Video

Updated: Jun 18, 2026

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

Published on: October 2, 2018

Hereditary osteodystrophy with multiple hormone resistance--a case report.

Ines Velez¹, Melanie Bond, Steven Ellen

¹Oral and Maxillofacial Pathology, Nova Southeastern University, College of Dental Medicine, USA. ivelez@nova.edu

The Journal of Clinical Pediatric Dentistry

|December 4, 2009

Summary

Pseudohypoparathyroidism (PHP) is a rare disorder causing hormone resistance. This case highlights how dental and jaw issues can lead to PHP diagnosis, preventing serious health implications.

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Last Updated: Jun 18, 2026

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

Published on: October 2, 2018

Area of Science:

Endocrinology
Genetics
Dentistry

Background:

Pseudohypoparathyroidism (PHP), a rare autosomal dominant disorder, involves resistance to multiple hormones despite adequate production.
PHP is characterized by a heterogeneous group of conditions, often presenting diagnostic challenges.

Observation:

The case highlights dental and jaw manifestations as key indicators of PHP.
Early diagnosis of PHP is crucial due to potential serious health implications.

Findings:

PHP was diagnosed in this patient based on dental and jaw abnormalities.
This case underscores the importance of considering PHP in patients with specific oral and maxillofacial presentations.

Implications:

Dentists can play a vital role in the early identification of rare genetic disorders like PHP.
Timely diagnosis through dental examination can mitigate the severe consequences associated with untreated PHP.