Related Experiment Video
Updated: Jun 18, 2026

Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery
Published on: October 20, 2023
[Experimental investigation of the intestine state in laparotomy, perforative peritonitis and ischemic-reperfusional
The changes of the small intestine wall, occurring under the influence of laparotomy, perforative peritonitis and ischemic-reperfusional trauma (IRT), were studied up in experimental conditions on laboratory rats. The material for the investigation (the intestinal portions and the blood) was gathered up on the second and the fifth day of the experiment. Alterative changes need the least time for restoration, the intestinal wall disorders in the perforative peritonitis conditions appear earlier, and gradually eliminate upon a time. The intestinal wall changes in IRT were the mostly significant, they had occurred later and needed more time for restoration.
The changes of the small intestine wall, occurring under the influence of laparotomy, perforative peritonitis and ischemic-reperfusional trauma (IRT), were studied up in experimental conditions on laboratory rats. The material for the investigation (the intestinal portions and the blood) was gathered up on the second and the fifth day of the experiment. Alterative changes need the least time for restoration, the intestinal wall disorders in the perforative peritonitis conditions appear earlier, and gradually eliminate upon a time. The intestinal wall changes in IRT were the mostly significant, they had occurred later and needed more time for restoration.

