Coi-wiz: An interactive computer wizard for analyzing cardiac optical signals.

Area of Science:

• Cardiac electrophysiology
• Biomedical imaging
• Computational biology

Background:

• Cardiac arrhythmias pose a significant challenge in cardiovascular medicine.
• Current analysis of high-resolution cardiac optical imaging data is time-consuming and manual.
• Advanced visualization and analysis tools are needed to improve understanding of arrhythmia mechanisms.

Purpose of the Study:

• To develop an interactive computer wizard for visualizing and analyzing high-resolution cardiac optical imaging data.
• To assist cardiac electrophysiology researchers in identifying arrhythmia mechanisms.
• To enhance the development of effective ablation strategies for cardiac arrhythmias.

Main Methods:

• Development of an interactive computer wizard with a user-friendly graphical interface (GUI).
• Implementation of a file interface supporting various data formats.
• Integration of analysis algorithms for spatial and temporal filtering, waveform generation, activation and action potential mapping, velocity field calculation, and heterogeneity measurement.

Main Results:

• The wizard facilitates efficient visualization and analysis of 3D cardiac optical imaging data.
• Automated generation of key electrophysiological parameters including waveforms, activation maps, and action potential maps.
• Interactive selection of regions of interest in both spatial and temporal domains for targeted analysis.

Conclusions:

• The developed interactive wizard significantly reduces the time and effort required for analyzing cardiac optical imaging data.
• This tool empowers researchers to better understand arrhythmia mechanisms and refine ablation strategies.
• The wizard supports the study of diverse cardiac chambers and electrophysiological phenomena.