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Updated: Jun 18, 2026
Simultaneous Electrophysiological Recording and Micro-injections of Inhibitory Agents in the Rodent Brain
Published on: July 7, 2015
Selective micro preconcentration of propofol for anesthetic depth monitoring by using seedless electroplated gold as
Bassam Alfeeli1, Mohammad A Zareian-Jahromi, Masoud Agah
1VTMEMS Laboratory, Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA. alfeeli@vt.edu
Abstract:
This communication presents selective preconcentration of the anesthetic agent (Propofol) and the elimination of unwanted species from a representative sample of human breath. In this approach, a micro preconcentrator (microPC) consisting of embedded high-aspect-ratio pillars (30 microm x 120 microm chi 240 microm), an outer dimensions of 7 mm x 7 mm (encompass more than 3500 micro pillars), total inner surface area of approximately 10 m(2), and a total inner volume of approximately 6.5 microL was used to selectively preconcentrate Propofol. The microPC has on-chip thermal desorption capability and was coated by electrodeposited gold as an adsorbent material. Experimental evaluations showed successful preconcentration of trace level of Propofol from a mixture containing several volatile organic compounds diluted in water-like solvent (1-propanol) and the efficient removal of non-polar compounds present in the mixture.
