Related Experiment Video
Updated: Jun 17, 2026

NMR 15N Relaxation Experiments for the Investigation of Picosecond to Nanoseconds Structural Dynamics of Proteins
Published on: November 1, 2024
Heteronuclear double resonance in nuclear magnetic resonance spectroscopy: Relaxation of multiple-quantum coherences
Simone Ulzega1, Mariachiara Verde, Fabien Ferrage
1Ecole Polytechnique Federale de Lausanne, Institut des Sciences et Ingenierie Chimiques, Lausanne 1015, Switzerland.
Abstract:
Theoretical and experimental investigations of the relaxation rates of multiple-quantum coherences during heteronuclear double resonance (HDR) pulse sequences are presented. Average Liouvillian theory yields analytical expressions to describe the effective relaxation rates of multiple-quantum coherences during HDR irradiation. Experiments were carried out on a (13)C-(1)H pair in glycerol to measure the effective auto- and cross-relaxation rates of multiple-quantum coherences during HDR schemes. The experimental results exhibit a very good agreement with theoretical predictions, even when the average Liouvillian expansion is truncated to zeroth order.
Related Concept Videos
2D NMR: Overview of Heteronuclear Correlation Techniques
Double Resonance Techniques: Overview
Spin decoupling is usually achieved by...
Atomic Nuclei: Types of Nuclear Relaxation
In spin–lattice or longitudinal relaxation, the excited spins exchange energy with the surrounding lattice as they return to the lower energy level. Among several mechanisms that contribute to spin–lattice relaxation, magnetic dipolar interactions are significant. Here, the excited nucleus transfers energy to a nearby...
2D NMR: Overview of Homonuclear Correlation Techniques
COSY90 is the standard two-dimensional (2D) COSY experiment that...
Atomic Nuclei: Nuclear Relaxation Processes
2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)

