Related Experiment Video
Updated: Jun 17, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Published on: January 7, 2019
Molecular evolution of measles viruses circulated in Taiwan 1992-2008
Wen-Yueh Cheng1, Lili Lee, Paul A Rota
1Research and Diagnostic Center, Centers for Disease Control, DOH, Taiwan. yueh@cdc.gov.tw
Abstract:
Genetic analyses of viral samples from 74 laboratory confirmed measles cases occurring in Taiwan during 1992-2008 identified six viral genotypes D3, D5, D9, G2, H1 and H2. The most frequently detected genotype, H1, was associated with outbreaks in 1994 and 2002, and was the likely indigenous genotype in 1992. In response to the outbreaks, two catch-up campaigns were launched and a routine second dose of measles, mumps, and rubella vaccine at entry to elementary school was introduced. The vaccination campaigns successfully reduced the number of measles cases in Taiwan, and many of the more recent cases can be traced to importations, primarily from other Asian countries. A number of measles genotypes which were associated with outbreaks in other Asian countries were detected among the more recent cases. The more recent genotype H1 viruses had sequences that were identical to those currently circulating in China or associated with international importation of virus.
Related Concept Videos
Viral Mutations
Evolution of Microbial Genome
Viral Recombination
Mutation, Gene Flow, and Genetic Drift
Single Nucleotide Polymorphisms-SNPs

