Related Experiment Videos
Effect of trabeculectomy on intraocular pressure fluctuation with postural change in eyes with open-angle glaucoma
Kazuyuki Hirooka1, Hirokazu Takenaka, Tetsuya Baba
1Department of Ophthalmology, Kagawa University Faculty of Medicine, Ikenobe, Miki, Kagawa, Japan. kazuyk@med.kagawa-u.ac.jp
Purpose:
To investigate the effect of trabeculectomy on the intraocular pressure (IOP) fluctuations caused by the postural change in patients with open-angle glaucoma.
Methods:
Prospective, nonrandomized study. Ten eyes of 10 patients with primary open-angle glaucoma and 3 eyes of 3 patients with normal-tension glaucoma who underwent trabeculectomy were studied. The IOP at the baseline and 3 months after trabeculectomy was measured in both sitting and supine positions. A pneumatonometer was used to measure the IOP in both sitting and supine position.
Results:
The mean IOP in the sitting position was 19.6+/-5.1 mm Hg at the baseline and 9.4+/-2.9 mm Hg after trabeculectomy (P<0.01, paired t test). The mean difference in IOP between the sitting and supine position was 4.1+/-1.6 mm Hg at the baseline and 2.2+/-1.5 mm Hg after trabeculectomy (P=0.01, paired t test).
Conclusions:
Trabeculectomy might decrease not only the IOP in the sitting position but also the magnitude of IOP elevation associated with the postural change.
Related Concept Videos
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Glaucoma: Overview
Ophthalmic Drug Delivery Systems
Increased Intracranial Pressure l: Introduction