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Related Concept Videos

Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Diversity of Protists IV01:27

Diversity of Protists IV

Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...
Diversity of Protists II01:27

Diversity of Protists II

Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...

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Analysis of the Epithelial Damage Produced by Entamoeba histolytica Infection
11:49

Analysis of the Epithelial Damage Produced by Entamoeba histolytica Infection

Published on: June 12, 2014

Amebiasis.

Karim A Alavi1

  • 1Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota, St. Paul, MN 55104, USA. alav0006@umn.edu

Clinics in Colon and Rectal Surgery
|December 17, 2009
PubMed
Summary
This summary is machine-generated.

Amebiasis, caused by Entamoema histolytica, is a major parasitic killer. Early medical treatment, including for asymptomatic carriers, is crucial to prevent severe outcomes like colitis and perforation.

Keywords:
Amebacolitisfulminantparasite

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Analysis of the Epithelial Damage Produced by Entamoeba histolytica Infection
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Area of Science:

  • Infectious Diseases
  • Parasitology
  • Global Health

Background:

  • Amebiasis is a significant global cause of parasitic disease mortality.
  • Entamoeba histolytica, the causative agent, exists in cyst and trophozoite forms.
  • Clinical manifestations range from asymptomatic carriage to severe colitis and perforation.

Purpose of the Study:

  • To highlight the clinical spectrum of amebiasis.
  • To emphasize the importance of early medical intervention.
  • To underscore the need for treating asymptomatic carriers.

Main Methods:

  • Review of clinical presentations of amebiasis.
  • Analysis of treatment outcomes for medical versus surgical management.
  • Evaluation of the impact of early diagnosis and treatment.

Main Results:

  • Most amebiasis cases are medically manageable.
  • A small subset requires urgent surgical intervention with high mortality.
  • Prompt medical therapy, including for carriers, reduces severe complications.

Conclusions:

  • Early recognition and medical treatment of amebiasis are vital.
  • Treatment of asymptomatic Entamoema histolytica carriers can prevent severe disease.
  • Aggressive management strategies are necessary for severe amebiasis cases.