Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-time electric-field neuronavigation on realistic head models for conventional and multi-locus TMS.

Brain stimulation·2026
Same author

Conductivity Deviations as Virtual Sources in Magnetoencephalography.

Brain topography·2026
Same author

Addressing population and neurobiological diversity in TMS-EEG biomarker research.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

TMS timed to interictal epileptiform discharges.

bioRxiv : the preprint server for biology·2026
Same author

Clinical utility and prospective of TMS-EEG: Updated review from an international expert group.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Distinct cortical excitability and connectivity profiles within the human SMA complex.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Jun 17, 2026

Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex
07:42

Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex

Published on: August 17, 2018

Methodology for combined TMS and EEG.

Risto J Ilmoniemi1, Dubravko Kicić

  • 1Department of Biomedical Engineering and Computational Science, Helsinki University of Technology, Finland. risto.ilmoniemi@tkk.fi

Brain Topography
|December 17, 2009
PubMed
Summary

Combining transcranial magnetic stimulation (TMS) with electroencephalography (EEG) non-invasively measures brain excitability and connectivity. Despite challenges with electromagnetic artifacts, TMS-EEG offers valuable insights into brain function.

More Related Videos

Extracting Visual Evoked Potentials from EEG Data Recorded During fMRI-guided Transcranial Magnetic Stimulation
09:36

Extracting Visual Evoked Potentials from EEG Data Recorded During fMRI-guided Transcranial Magnetic Stimulation

Published on: May 12, 2014

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
08:23

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

Related Experiment Videos

Last Updated: Jun 17, 2026

Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex
07:42

Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex

Published on: August 17, 2018

Extracting Visual Evoked Potentials from EEG Data Recorded During fMRI-guided Transcranial Magnetic Stimulation
09:36

Extracting Visual Evoked Potentials from EEG Data Recorded During fMRI-guided Transcranial Magnetic Stimulation

Published on: May 12, 2014

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
08:23

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

Area of Science:

  • Neuroscience
  • Brain-Computer Interfaces
  • Electrophysiology

Background:

  • Transcranial magnetic stimulation (TMS) combined with electroencephalography (EEG) offers a non-invasive method to study brain function.
  • Early TMS-EEG research was hindered by significant electromagnetic artifacts induced by TMS pulses.
  • Development of TMS-compatible EEG systems has aimed to mitigate these artifact issues.

Purpose of the Study:

  • To explore the capabilities of combined TMS-EEG for non-invasively probing brain excitability, connectivity, and instantaneous states.
  • To address the persistent challenges and artifact sources in TMS-EEG recordings.
  • To validate the utility of TMS-EEG in providing meaningful neurophysiological data.

Main Methods:

  • Utilizing TMS-compatible EEG systems designed to minimize pulse-induced electromagnetic artifacts.
  • Implementing careful experimental precautions to avoid artifact sources like electrode movement and muscle activation.
  • Employing filtering techniques and control experiments to isolate genuine brain responses from residual artifacts.

Main Results:

  • Despite artifact challenges, TMS-EEG can successfully measure brain excitability and time-resolved connectivity.
  • Identified various artifact sources including electrode movement, muscle activation, eye movements, electrode polarization, and coil click responses.
  • Demonstrated that with careful methodology, artifacts can be managed to yield valuable neurophysiological data.

Conclusions:

  • TMS-EEG is a powerful non-invasive technique for investigating brain excitability and connectivity.
  • Overcoming electromagnetic artifacts is crucial for reliable TMS-EEG data acquisition.
  • Further research and methodological refinement will enhance the application of TMS-EEG in neuroscience.