Application of Bayesian classification with singular value decomposition method in genome-wide association studies.

Soonil Kwon1, Jinrui Cui, Shannon L Rhodes

  • 1Medical Genetics Institute, Cedars-Sinai Medical Center, 8635 West Third Street, Los Angeles, CA 90048, USA. Soonil.Kwon@cshs.org.

BMC Proceedings
|December 19, 2009
PubMed
Summary

We developed a faster Bayesian classification with singular value decomposition (BCSVD) method to efficiently analyze genetic data from genome-wide association studies (GWAS). This improved method accurately identifies genetic markers associated with diseases like rheumatoid arthritis.

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