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Updated: Jun 17, 2026

Three-Dimensional Modeling of the Left Atrium and Pulmonary Veins with a Precise Intracardiac Echocardiography Approach
Published on: June 30, 2023
Anatomy of the left atrium for interventional electrophysiologists
Siew Yen Ho1, Karen P McCarthy
1National Heart & Lung Institute, Imperial College London, London, UK. yen.ho@imperial.ac.uk
Insights
This study reviews left atrial anatomy crucial for interventional procedures. Understanding the left atrium
Area of Science:
- Cardiovascular Anatomy
- Interventional Cardiology
Background:
- Interventional procedures increasingly require left atrial access from both internal and pericardial spaces.
- Key anatomical structures surrounding the left atrium, including nerves and the esophagus, are critical considerations.
Purpose of the Study:
- To review the anatomical components of the left atrium relevant to interventional electrophysiologists.
- To highlight specific features of the atrial septum, mitral isthmus, and atrial walls.
Main Methods:
- Review of anatomical literature focusing on the left atrium.
- Emphasis on structures pertinent to interventional procedures.
Main Results:
- Detailed description of the left atrial septum, ridge, mitral isthmus, and walls.
- Identification of common anatomical variations like pits and crevices.
- Mapping of interatrial muscular connections, including Bachmann's bundle and venous sleeves.
Conclusions:
- Comprehensive understanding of left atrial anatomy is vital for safe and effective interventional procedures.
- Awareness of phrenic nerve and esophageal proximity is essential.
- Detailed anatomical knowledge aids electrophysiologists in navigating complex cardiac structures.
Abstract:
Increasingly, interventional procedures require accessing the left atrium from the inside of the heart as well as from the pericardial space. The right phrenic nerve running along the fibrous pericardium is close to the atrial insertion of the right superior pulmonary vein while the left phrenic nerve passes over the left atrial appendage. Posteriorly, the esophagus descends adjacent to the fibrous pericardium covering the posterior and postero-inferior walls of the left atrium. The component parts of the left atrium are reviewed with emphasis on the structure of the atrial septum, the left atrial ridge, the mitral isthmus, and the left atrial walls. Although the atrial walls are mainly smooth, pits and crevices are common in the region of the mitral isthmus and the vicinity of the os of the atrial appendage. The muscular rim around the valve of the oval fossa delimits the extent of the true atrial septum. Interatrial muscular connections exist at the septum, along Bachmann's bundle and also at the muscular sleeves of the coronary sinus and pulmonary veins. Anatomical features relevant to interventional electrophysiologists are highlighted.
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