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Updated: Jun 17, 2026

Intrauterine Telemetry to Measure Mouse Contractile Pressure In Vivo
07:03

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Published on: April 6, 2015

Term labor induction compared with expectant management.

J Christopher Glantz1

  • 1From the University of Rochester School of Medicine, Rochester, New York.

Obstetrics and Gynecology
|December 23, 2009
PubMed
Summary
This summary is machine-generated.

Labor induction is linked to a higher risk of cesarean delivery, even when compared to different expectant management groups. Women should be informed about this increased risk, which is approximately 1-2 extra cesarean deliveries per 25 inductions.

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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Reproductive Health

Background:

  • Labor induction is a common obstetric intervention.
  • The association between labor induction and cesarean delivery risk is debated.
  • Comparison group definitions may influence study outcomes.

Purpose of the Study:

  • To investigate how different comparison groups affect the association between labor induction and cesarean delivery risk.
  • To determine if the observed increased cesarean risk with induction is robust across various analytical approaches.

Main Methods:

  • Utilized a New York State birth-certificate database for a retrospective analysis.
  • Estimated odds ratios for cesarean delivery comparing induction with three control group definitions: week-to-week, all above, and at or above.
  • Employed chi-square logistic regression, adjusting for confounders like parity and high-risk factors.

Main Results:

  • All comparison methods showed an unadjusted increased cesarean risk post-induction, except for the 'all above' group after 39 weeks.
  • Adjusted analyses revealed persistent increased risk from 37-41 weeks (week-to-week) and 38-41 weeks (at or above), with odds ratios ranging from 1.24 to 1.45.
  • The 'all above' group no longer showed a significant increased risk after adjustment.

Conclusions:

  • Labor induction is associated with an increased risk of cesarean delivery, irrespective of the comparison group used (week-to-week or expectant management).
  • This association remains significant even after adjusting for key demographic and clinical confounders.
  • While the absolute increase in risk per woman is modest, informed consent regarding this potential outcome is crucial.