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Updated: Jun 17, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Clinical analysis on 14 cases with malignant melanoma in nasal cavity and sinus]
Yinzhou Xiang1, Ping Peng, Lianzhi Wei
1Department of Otolaryngology, the First Hospital of Yichang, Yichang, 443000, China. xiangyinzhou@sina.com
Objective:
To investigate the effect of treatment on malignant melanoma in nasal cavity and paranasal sinus.
Method:
Fourteen patients with malignant melanoma in nasal cavity and paranasal sinus were retrospectively analyzed from 1995 to 2002, including clinical presentation, diagnosis, treatment and follow-up data.
Result:
Thirteen patients were followed up, the survival rates of 3 and 5 years were 42.9% and 21.4% respectively.
Conclusion:
Sinonasal malignant melanoma has an aggressive behavior and easy recurrence. Early diagnosis, radical operation and postoperative radiotherapy could improve the survival rate.