Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 17, 2026

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
10:52

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence

Published on: December 23, 2022

Vascular closure device failure: frequency and implications: a propensity-matched analysis.

Sripal Bangalore1, Nipun Arora, Frederic S Resnic

  • 1Division of Cardiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Circulation. Cardiovascular Interventions
|December 25, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Statistical Framework to Detect and Quantify Operator-Learning Curves in Medical Device Safety Evaluation.

Medical devices (Auckland, N.Z.)·2025
Same author

A machine learning framework to adjust for learning effects in medical device safety evaluation.

Journal of the American Medical Informatics Association : JAMIA·2024
Same author

Real Data Applications of Learning Curves In Cardiac Devices and Procedures.

Journal of medical statistics and informatics·2024
Same author

A Comprehensive Framework for Evaluating the Value Created by Real-World Evidence for Diverse Stakeholders: The Case for Coordinated Registry Networks.

Therapeutic innovation & regulatory science·2024
Same author

Spontaneous Migration of Ventriculoperitoneal Shunt Into the Right Heart and Pulmonary Vasculature.

JACC. Case reports·2024
Same author

Testing a Cloud-Based Model for Active Surveillance of Medical Devices with Analyses of Coronary Stent Safety Using the Data Extraction and Longitudinal Trend Analysis (DELTA) System.

Medical devices (Auckland, N.Z.)·2024
Same journal

Pullback Pressure Gradient and Intravascular Imaging in Focal and Diffuse Coronary Disease: The Next Step in Precision PCI?

Circulation. Cardiovascular interventions·2026
Same journal

Risk of Aortic Root Rupture in Bicuspid Aortic Stenosis: The ABC Sizing Algorithm for SAPIEN 3 Valves.

Circulation. Cardiovascular interventions·2026
Same journal

Transcatheter Mitral Valve-in-Valve: Optimal Sizing and Expansion Matter.

Circulation. Cardiovascular interventions·2026
Same journal

Nicorandil to Prevent Contrast-Associated Kidney Injury in High-Risk PCI.

Circulation. Cardiovascular interventions·2026
Same journal

Prospective Midterm Outcomes of the PULSTA Self-Expandable Transcatheter Pulmonary Valve: The PULSTA CE Approval Study.

Circulation. Cardiovascular interventions·2026
Same journal

Is There a Golden Hour for Thrombectomy in Intermediate-Risk Pulmonary Embolism? Insights From SYMPHONY-PE.

Circulation. Cardiovascular interventions·2026
See all related articles

Vascular closure device (VCD) failure is rare, occurring in 2.7% of cases. However, VCD failure significantly increases the risk of vascular complications, necessitating close patient monitoring.

Area of Science:

  • Cardiology
  • Vascular Surgery
  • Medical Devices

Background:

  • Vascular closure devices (VCDs) are widely used after cardiac catheterization to improve patient outcomes.
  • The frequency and consequences of VCD failure remain incompletely understood.

Purpose of the Study:

  • To define the incidence and clinical sequelae of VCD failure in a large patient cohort.
  • To assess the association between VCD failure and vascular complications.

Main Methods:

  • A prospective registry of 9823 patients undergoing cardiac catheterization using collagen plug-based (Angio-Seal) or suture-based (Perclose) VCDs was analyzed.
  • VCD failure was defined as unsuccessful deployment or failure to achieve hemostasis.
  • Vascular complications were categorized as major, minor, or any, and compared between successful and failed VCD deployments.

More Related Videos

In Vitro Thrombosis Test for Ventricular Assist Devices
09:15

In Vitro Thrombosis Test for Ventricular Assist Devices

Published on: March 21, 2025

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

Related Experiment Videos

Last Updated: Jun 17, 2026

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
10:52

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence

Published on: December 23, 2022

In Vitro Thrombosis Test for Ventricular Assist Devices
09:15

In Vitro Thrombosis Test for Ventricular Assist Devices

Published on: March 21, 2025

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

Main Results:

  • VCD failure occurred in 2.7% of patients (268/9823), with a higher incidence in percutaneous coronary intervention (3.0%) versus diagnostic procedures (2.3%).
  • Patients experiencing VCD failure had a significantly increased risk of any vascular complication (6.7% vs. 1.4%), major complication (1.9% vs. 0.6%), and minor complication (6.0% vs. 1.1%).
  • This increased risk of vascular complications associated with VCD failure persisted even after propensity score matching.

Conclusions:

  • Vascular closure device failure is an infrequent event in current clinical practice.
  • Despite its rarity, VCD failure is strongly associated with a substantial rise in the risk of vascular complications.
  • Close monitoring of patients experiencing VCD failure is crucial to manage potential complications effectively.