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Updated: Jun 17, 2026

Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood
13:14

Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood

Published on: February 6, 2018

[Therapeutic monoclonal antibodies: knowledge transfer from Inserm]

Mallory Perrin-Wolff1, Christophe Cans

  • 1Inserm Transfert, Paris Biopark, 7 rue Watt, 75013 Paris, France. mallory.wolff@inserm-transfert.fr

Medecine Sciences : M/S
|December 29, 2009
PubMed
Summary

No abstract available in PubMed .

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Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...