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Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
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Star-shaped azomethines based on tris(2-aminoethyl)amine. Characterization, thermal and optical study

Agnieszka Iwan1, Henryk Janeczek, Bozena Kaczmarczyk

  • 1Electrotechnical Institute, Division of Electrotechnology and Materials Science, M Sklodowskiej-Curie 55/61 Street, 50-369 Wroclaw, Poland. a.iwan@iel.wroc.pl

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
|December 29, 2009
PubMed

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Direct alkylation of ammonia produces polyalkylated amines, along with a quaternary ammonium salt. To exclusively prepare primary amines, the azide synthesis method can be used.
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Direct alkylation is not a suitable method for synthesizing amines because it produces polyalkylated products. Gabriel synthesis is the most preferred method to exclusively make primary amines. The method uses phthalimide, which contains a protected form of nitrogen that participates in alkylation only once to predominantly give primary amines.
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