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Related Concept Videos

Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Inflammatory Response01:28

Inflammatory Response

An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
Inflammation01:38

Inflammation

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Related Experiment Video

Updated: Jun 17, 2026

Evaluation of Changes in Hydration and Body Cell Mass with Bioelectrical Impedance Analysis after Exercise Program for Rheumatoid Arthritis Patients
07:44

Evaluation of Changes in Hydration and Body Cell Mass with Bioelectrical Impedance Analysis after Exercise Program for Rheumatoid Arthritis Patients

Published on: July 14, 2023

Persistent low-grade inflammation and regular exercise.

Maj-Briit Astrom1, Michael Feigh, Bente Klarlund Pedersen

  • 1Department of Infectious Diseases and CMRC Copenhagen University Hospital, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, The Centre of Inflammation and Metabolism, Copenhagen, Denmark.

Frontiers in Bioscience (Scholar Edition)
|December 29, 2009
PubMed
Summary
This summary is machine-generated.

Regular exercise combats chronic diseases by reducing inflammation. Exercise may lower inflammation by decreasing visceral fat or increasing anti-inflammatory cytokines.

Related Experiment Videos

Last Updated: Jun 17, 2026

Evaluation of Changes in Hydration and Body Cell Mass with Bioelectrical Impedance Analysis after Exercise Program for Rheumatoid Arthritis Patients
07:44

Evaluation of Changes in Hydration and Body Cell Mass with Bioelectrical Impedance Analysis after Exercise Program for Rheumatoid Arthritis Patients

Published on: July 14, 2023

Area of Science:

  • Exercise physiology
  • Immunology
  • Metabolic disease research

Background:

  • Persistent low-grade systemic inflammation is linked to chronic diseases like cardiovascular disease (CVD), type 2 diabetes, and dementia.
  • Inflammation is a causal factor in insulin resistance and atherosclerosis.
  • Visceral adiposity is a key contributor to systemic inflammation and disease risk.

Purpose of the Study:

  • To explore the anti-inflammatory effects of regular exercise.
  • To investigate exercise's role in mitigating chronic disease risk.
  • To elucidate mechanisms behind exercise-induced anti-inflammatory effects.

Main Methods:

  • Review of existing evidence on exercise, inflammation, and chronic diseases.
  • Analysis of the relationship between visceral adiposity and systemic inflammation.
  • Hypothesizing mechanisms of exercise's anti-inflammatory action.

Main Results:

  • Regular exercise demonstrates protective effects against CVD, type 2 diabetes, and dementia.
  • Exercise's benefits are partly attributed to its anti-inflammatory properties.
  • Exercise may reduce inflammation through visceral fat reduction and cytokine induction.

Conclusions:

  • Exercise exerts anti-inflammatory effects that contribute to its protective role in chronic diseases.
  • Mechanisms include long-term reduction in visceral fat mass and acute induction of anti-inflammatory cytokines.
  • Regular physical activity is a viable strategy for managing and preventing inflammatory chronic conditions.