Related Experiment Video

Updated: Jun 17, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Published on: December 14, 2020

[Oral acid-basic balance peculiarities in patients with gastrointestinal tract pathology]

V A Rumiantsev, L K Esaian, O O Tolstova

    Stomatologiia
    |December 29, 2009
    PubMed

    More Related Videos

    Profiling Luminal pH in Three-Dimensional Gastrointestinal Organoids Using Microelectrodes08:24

    Profiling Luminal pH in Three-Dimensional Gastrointestinal Organoids Using Microelectrodes

    Published on: July 5, 2024

    Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells10:18

    Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells

    Published on: June 13, 2019

    Related Concept Videos

    Disorders of Acid-Base Balance01:29

    Disorders of Acid-Base Balance

    The human body maintains a precise pH range of arterial blood between 7.35 and 7.45. Deviations result in either acidosis (pH < 7.35) or alkalosis (pH > 7.45). These conditions are further classified as respiratory or metabolic disorders based on their underlying cause.
    Respiratory Acidosis and Alkalosis
    Respiratory acidosis occurs due to an increase in the partial pressure of carbon dioxide PCO2 in the blood. It often arises from shallow breathing or impaired gas exchange caused by...
    Diagnosing Acidosis and Alkalosis01:24

    Diagnosing Acidosis and Alkalosis

    Diagnosing acid-base imbalances involves systematically analyzing arterial blood samples, focusing on three key measurements: pH, bicarbonate (HCO3−) concentration, and carbon dioxide partial pressure (PCO2). This analysis follows a four-step process that helps identify the imbalance's underlying cause and nature.
    First, the pH level is assessed to determine whether the blood pH is normal (7.35–7.45), low (acidosis), or high (alkalosis).
    Next, the PCO2  and HCO3−  values are examined to...
    Acid-Base Balance01:25

    Acid-Base Balance

    The human body maintains a narrow pH range regulated through acid-base balance. This balance is crucial as changes in the hydrogen ion concentration can disrupt cell membrane stability, alter protein structures, and change enzyme activities. The normal pH of arterial blood is 7.4, venous blood and interstitial fluid is 7.35, and intracellular fluid averages 7.0.
    When the pH of arterial blood rises above 7.45, it results in a condition called alkalosis. Conversely, a drop below 7.35 leads to...
    pH Homeostasis01:31

    pH Homeostasis

    Acid-base homeostasis is essential for maintaining normal physiological activities in humans. The pH of various body fluids is strictly regulated because it is critical for the optimal activity of enzymes involved in metabolic reactions. Enzymes are basically proteins, so, any significant change in pH can affect their structure and activity. In humans, pH is regulated using three primary mechanisms— chemical buffer systems, respiratory regulation, and renal regulation.
    Respiratory Regulation of...
    Stomach pH Regulation01:21

    Stomach pH Regulation

    The human body carefully regulates the internal pH of different organs to maintain homeostasis. For example, while the blood plasma maintains a neutral pH of 7, the stomach lumen has an acidic pH of 1.5 - 3.5. The low pH of stomach lumen helps kill pathogens in the food and break down complex food molecules.
    The acid-secreting gastric mucosal epithelial cells (parietal cells) lining the stomach lumen maintain the low pH in the lumen. Numerous ion transporters and channels on these parietal...
    Acid Suppressive Drugs for Peptic Ulcer Disease: Antacids01:31

    Acid Suppressive Drugs for Peptic Ulcer Disease: Antacids

    In the complex environment of the gastric lumen, excessive acid secretion can lead to the formation or worsening of ulcers within the delicate mucosal layer. Antacids, such as sodium bicarbonate and calcium carbonate, provide relief by neutralizing this acid, transforming it into harmless salt and water. This neutralization process raises the gastric pH from a highly acidic level of 1 to a more basic 3-4, reducing the acidity within the stomach.
    However, this neutralization reaction between...