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Updated: Jun 17, 2026

Simultaneous Electrophysiological Recording and Micro-injections of Inhibitory Agents in the Rodent Brain
Published on: July 7, 2015
[Simultaneous injection of lidocaine improves predictability of effect of botulinum toxin]
Abstract:
Injection of botulinum toxin A is a common procedure in Otorhinolaryngology, Ophtalmology and Neurolgy. Recently botulinum toxin treatment has been described to improve woundhealing after facial injuries. The lack of immediate predictibility of the ensuing paralytic effect is one of the daily challenges of botulinum toxin injections. In the present report we describe the simultaneous injection of botulinum toxin and lidocaine with the purpose to gain immediate feed back of the treatment effect. Furthermore we recommend the addition of adrenalin to reduce possible systemical toxin circulation.
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