Related Experiment Video
Updated: Jun 17, 2026

06:12
Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets
Published on: March 17, 2023
Design and optimization of a novel surface plasmon resonance biosensor based on Otto configuration
E K Akowuah1, T Gorman, S Haxha
1Broadband and Wireless Communication group, Department of Electronics, University of Kent, Canterbury, CT2 7NT, UK.
Optics Express
|January 7, 2010
Summary
This study presents a novel planar waveguide surface Plasmon Biosensor. The biosensor achieves a high resolution of 2.3 x 10(-6) RIU for aqueous analytes, showcasing its potential for sensitive detection.
Area of Science:
- Photonics and optical sensing
- Nanotechnology and plasmonics
- Biomedical engineering
Background:
- Surface Plasmon Polaritons (SPPs) offer label-free detection capabilities.
- Waveguide-based biosensors are crucial for sensitive analyte detection.
- The Otto excitation mechanism is a known method for SPP generation.
Purpose of the Study:
- To theoretically investigate a novel planar waveguide surface Plasmon Biosensor.
- To analyze the impact of key parameters like gap-width and device length on biosensor performance.
- To demonstrate the biosensor's resolution for aqueous analytes.
Main Methods:
- Theoretical modeling of a planar waveguide surface Plasmon Biosensor.
- Utilizing an eigenmode solver with perfectly matched layers (PML).
- Investigating the influence of system parameters on device performance.
Main Results:
- The proposed biosensor design is based on the Otto excitation mechanism.
- Performance analysis focused on gap-width and device length.
- Achieved a high resolution of 2.3 x 10(-6) RIU for aqueous analytes.
Conclusions:
- The novel planar waveguide biosensor shows promising performance.
- The theoretical investigation validates the design and parameter influence.
- The demonstrated resolution indicates potential for sensitive biosensing applications.
