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Acute post-streptococcal glomerulonephritis.

J Richards1

  • 1West Virginia University Health Sciences Center.

The West Virginia Medical Journal
|February 1, 1991
PubMed
Summary
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Acute post-streptococcal glomerulonephritis, a kidney inflammation following strep infections, typically affects children and resolves with supportive care. While usually benign in kids, adults may face lasting kidney issues like hypertension.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Pediatrics

Background:

  • Acute glomerulonephritis presents with hematuria, proteinuria, edema, and potential renal failure.
  • Acute post-streptococcal glomerulonephritis is a primary example of acute glomerulonephritis.

Observation:

  • This condition follows streptococcal pharyngeal or skin infections, with incubation periods of 7-14 and 14-21 days, respectively.
  • It predominantly affects young children, accounting for about 90% of cases.

Findings:

  • Diagnosis relies on evidence of recent streptococcal infection, confirmed by positive ASO-titer or Anti-DNAase B titer, and hypocomplementemia.
  • The disease is self-limiting, typically resolving within weeks to months with supportive therapy.

Implications:

Related Experiment Videos

  • Children generally experience no permanent sequelae.
  • Adults may have an increased risk of developing hypertension and chronic renal failure.