Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcriptomic Analysis of Metastatic Uveal Melanoma and Differences in Male and Female Patients.

Cancer genomics & proteomicsยท2024
Same author

Specific binding sites on Rhesus rotavirus capsid protein dictate the method of endocytosis inducing the murine model of biliary atresia.

American journal of physiology. Gastrointestinal and liver physiologyยท2024
Same author

Targeting MYC at the intersection between cancer metabolism and oncoimmunology.

Frontiers in immunologyยท2024
Same author

Rhesus rotavirus receptor-binding site affects high mobility group box 1 release, altering the pathogenesis ofย experimental biliary atresia.

Hepatology communicationsยท2022
Same author

Assessing the effects of antipsychotic medications on schizophrenia functional analysis: a postmortem proteome study.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacologyยท2022
Same author

KRSA: An R package and R Shiny web application for an end-to-end upstream kinase analysis of kinome array data.

PloS oneยท2021
Same journal

pGWAS-Portal: a comprehensive online platform for integrative post-genome-wide association study analysis.

BMC genomicsยท2026
Same journal

Physiological and transcriptomic analyses of Rosa persica in response to drought stress and functional validation of the transcription factor RpERF113-like.

BMC genomicsยท2026
Same journal

Integrated analysis of chromatin accessibility and transcriptome profiles in granulosa cells of sheep with different FecB genotypes.

BMC genomicsยท2026
Same journal

Correction: TB-DROP: deep learning-based drug resistance prediction of Mycobacterium tuberculosis utilizing whole genome mutations.

BMC genomicsยท2026
Same journal

Chromosomal scale genome assembly of medicinal plant Sophora tonkinensis.

BMC genomicsยท2026
Same journal

Variant-specific RNA testing resolves variants of uncertain significance in exome testing.

BMC genomicsยท2026
See all related articles

Related Experiment Video

Updated: Jun 17, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

Genomics Portals: integrative web-platform for mining genomics data.

Kaustubh Shinde1, Mukta Phatak, Freudenberg M Johannes

  • 1Laboratory for Statistical Genomics and Systems Biology, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati OH 45267-0056, USA.

BMC Genomics
|January 15, 2010
PubMed
Summary
This summary is machine-generated.

Genomics Portals integrates vast public genomics data with a knowledge base and analytical tools. This platform aids researchers in interpreting experimental results and mining large datasets for new biological insights.

More Related Videos

Introductory Analysis and Validation of CUT&RUN Sequencing Data
04:58

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Published on: December 13, 2024

Related Experiment Videos

Last Updated: Jun 17, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

Introductory Analysis and Validation of CUT&RUN Sequencing Data
04:58

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Published on: December 13, 2024

Area of Science:

  • Genomics and Bioinformatics
  • Systems Biology

Background:

  • High-throughput technologies generate extensive experimental data, available in public repositories.
  • Knowledge of molecular networks, pathways, and regulatory modules is rapidly expanding.
  • Integrating public data and functional knowledge offers potential for novel biological insights.

Purpose of the Study:

  • To present the Genomics Portals platform for integrated access to genomics data and knowledge.
  • To provide tools for analyzing and interpreting experimental data within a broader biological context.
  • To facilitate effective mining of large-scale public genomics datasets.

Main Methods:

  • Integration of a comprehensive knowledge base with a large database of human, mouse, and rat genomics data.
  • Inclusion of basic analytical and visualization tools.
  • Access to diverse genomics data types including gene expression, ChIP-chip, ChIP-seq, and epigenomics.

Main Results:

  • The Genomics Portals platform offers integrated access to extensive genomics data and a knowledge base.
  • It provides tools for analyzing and interpreting new experimental data.
  • The platform uniquely combines data volume, diversity, and knowledge integration for biological analysis.

Conclusions:

  • Genomics Portals provides a unique tool for interpreting genomics experiments and mining public data.
  • Integrated access to data, knowledge, and tools enhances biological discovery.
  • The platform is freely accessible at http://GenomicsPortals.org.