Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

Chronic Inflammation: Introduction

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Inflammatory Bowel Disease II: Crohn's Disease

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Modelling of onchocerciasis-associated skin and ocular disease and the impact of ivermectin treatment.

Communications medicine·2026

Same author

Strengthening dermatology capacity and competency in resource-limited settings: A viewpoint.

PLoS neglected tropical diseases·2025

Same author

A global call for action to tackle skin-related neglected tropical diseases (skin NTDs) through integration: An ambitious step change.

PLoS neglected tropical diseases·2023

Same author

World Health Organization strategic framework for integrated control and management of skin-related neglected tropical diseases: what does this mean for dermatologists?

The British journal of dermatology·2023

Same author

The burden of skin disease and eye disease due to onchocerciasis in countries formerly under the African Programme for Onchocerciasis Control mandate for 1990, 2020, and 2030.

PLoS neglected tropical diseases·2021

Same author

How does onchocerciasis-related skin and eye disease in Africa depend on cumulative exposure to infection and mass treatment?

PLoS neglected tropical diseases·2021

Same journal

Use of gloves: current evidence vs. current use.

Current opinion in infectious diseases·2026

Same journal

Understanding challenges to prevention of healthcare related infections.

Current opinion in infectious diseases·2026

Same journal

Harnessing next-generation microbial diagnostics to optimize infection management in immunocompromised hosts.

Current opinion in infectious diseases·2026

Same journal

Epidemiology, treatment and outcomes of antimicrobial-resistant infections in hematopoietic stem cell transplant recipients.

Current opinion in infectious diseases·2026

Same journal

Dengue and chikungunya vaccines past, present and future: implications for travelers.

Current opinion in infectious diseases·2026

Same journal

Oropouche virus: viral evolution, epidemiological trends, and challenges for control.

Current opinion in infectious diseases·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 17, 2026

A Rat Model of Compound Acne

A Rat Model of Compound Acne

Published on: November 1, 2024

Onchodermatitis.

Michele E Murdoch¹

¹Watford General Hospital, Watford, UK. michele.murdoch@whht.nhs.uk

Current Opinion in Infectious Diseases

|January 15, 2010

Summary

This summary is machine-generated.

Onchodermatitis control has advanced with new treatments like doxycycline and moxidectin, alongside ivermectin. Disease transmission elimination is nearing, but long-term ivermectin impacts and new drug targets require further research.

More Related Videos

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

Related Experiment Videos

Last Updated: Jun 17, 2026

A Rat Model of Compound Acne

A Rat Model of Compound Acne

Published on: November 1, 2024

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

Area of Science:

Tropical Medicine
Infectious Diseases
Dermatology

Background:

Onchodermatitis disease burden awareness has grown significantly.
Recent advancements focus on immunopathogenesis, diagnosis, and treatment strategies.

Purpose of the Study:

To review recent progress in onchodermatitis control.
Emphasis on publications from the past two years.

Main Methods:

Review of recent scientific literature on onchodermatitis.
Analysis of treatment strategies including ivermectin, doxycycline, and moxidectin.

Main Results:

The African Programme for Onchocerciasis Control (APOC) now covers 19 African countries with community-directed treatment with ivermectin (CDTI).
Doxycycline and moxidectin show promise as alternative or complementary treatments to ivermectin.
Transmission interruption achieved in half of Latin American foci, with Colombia leading countrywide interruption.

Conclusions:

Large-scale ivermectin distribution impacts are pending.
Further research into Wolbachia metabolic pathways for new drug targets is crucial.
Disease transmission elimination is achievable but requires more research on optimal ivermectin cessation strategies.