Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficient Gene Editing for Heart Disease via ELIP-Based CRISPR Delivery System.

Pharmaceutics·2024
Same author

An Echogenic Clot Method for Thrombolysis Monitoring in Thrombotic Stroke Models.

Medical research archives·2023
Same author

Storage Stability of Atheroglitatide, an Echogenic Liposomal Formulation of Pioglitazone Targeted to Advanced Atheroma with a Fibrin-Binding Peptide.

Pharmaceutics·2023
Same author

Enhanced Cerebroprotection of Xenon-Loaded Liposomes in Combination with rtPA Thrombolysis for Embolic Ischemic Stroke.

Biomolecules·2023
Same author

Liposome-Based Carriers for CRISPR Genome Editing.

International journal of molecular sciences·2023
Same author

Whey protein powder with milk fat globule membrane attenuates Alzheimer's disease pathology in 3×Tg-AD mice by modulating neuroinflammation through the peroxisome proliferator-activated receptor γ signaling pathway.

Journal of dairy science·2023
Same journal

Isolation of Mesenchymal Stem Cell-Derived Extracellular Vesicles.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Modeling Melanoma Immune Surveillance by CAR-T Cells in Human Skin Organoids.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Stepwise Optimization of a Matrigel-Based In Vitro Angiogenesis Assay for Reproducible and Quantifiable 2D-Tube Formation Using HUVECs.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Quantifying Mechanical Properties of Fresh Ovarian Tissue with Optical Brillouin Microscopy.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

3D Chromatin Architecture During Early Development: New Methods and New Findings.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Metabolic Plasticity in Embryogenesis Throughout the Lens of NAD<sup></sup>.

Methods in molecular biology (Clifton, N.J.)·2026
See all related articles

Related Experiment Video

Updated: Jun 17, 2026

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes
09:51

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Published on: March 3, 2020

Ultrasound-responsive liposomes.

Shao-Ling Huang1

  • 1Cardiology Division, Department of Internal Medicine, University of Texas Health Science Center, Houston, TX, USA.

Methods in Molecular Biology (Clifton, N.J.)
|January 15, 2010
PubMed
Summary
This summary is machine-generated.

Ultrasound-responsive liposomes encapsulate gas and drugs for imaging and targeted release. This technology enables precise drug delivery, minimizing systemic side effects for various conditions.

More Related Videos

Synthesis of Gold Nanoparticle Integrated Photo-responsive Liposomes and Measurement of Their Microbubble Cavitation upon Pulse Laser Excitation
12:00

Synthesis of Gold Nanoparticle Integrated Photo-responsive Liposomes and Measurement of Their Microbubble Cavitation upon Pulse Laser Excitation

Published on: February 24, 2016

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation
08:28

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation

Published on: September 13, 2012

Related Experiment Videos

Last Updated: Jun 17, 2026

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes
09:51

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Published on: March 3, 2020

Synthesis of Gold Nanoparticle Integrated Photo-responsive Liposomes and Measurement of Their Microbubble Cavitation upon Pulse Laser Excitation
12:00

Synthesis of Gold Nanoparticle Integrated Photo-responsive Liposomes and Measurement of Their Microbubble Cavitation upon Pulse Laser Excitation

Published on: February 24, 2016

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation
08:28

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation

Published on: September 13, 2012

Area of Science:

  • Biotechnology
  • Nanomedicine
  • Drug Delivery Systems

Background:

  • Ultrasound-responsive liposomes integrate gas, enabling acoustic activity and controlled release via ultrasound stimulation.
  • Co-encapsulation of pharmaceuticals with gas enhances liposome functionality for combined imaging and therapeutic applications.

Purpose of the Study:

  • To detail facile production methods for gas-containing liposomes with simultaneous drug encapsulation.
  • To highlight the potential of ultrasound-mediated drug delivery for localized treatment of various clinical conditions.

Main Methods:

  • Liposomes prepared using conventional methods (phospholipid, cholesterol hydration, sonication).
  • Gas introduction via two methods: freezing/lyophilization with mannitol or freezing under elevated gas pressure.
  • Mannitol accentuates freezing damage to lipid membranes, facilitating gas incorporation.

Main Results:

  • Demonstrated facile production of gas-containing liposomes with simultaneous drug encapsulation.
  • Established methods for introducing gas into liposomes post-sonication.

Conclusions:

  • Ultrasound-responsive liposomes offer a promising platform for targeted drug delivery.
  • Potential applications span cancer, thrombus, arterial restenosis, myocardial infarction, and angiogenesis, improving treatment efficacy and reducing systemic toxicity.