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Updated: Jun 16, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
Published on: June 6, 2025
[Increased risk of suicide in patients with agitated depression]
Abstract:
In our study we aimed to verify the clinical features of agitated depression, which intensify suicidal trends leading to completed suicide. From 477 patients with agitated depression we selected 126, who presented high risk of suicide and studded them by using Mood Anxiety Inventory. On the bases of the structural-dynamic analyses we determine seven clinical variations of agitated-depression with prominent affective, cognitive, psychomotor, somato-algetic and behavioral symptoms. The most dangerous types with regards of suicidal behavior appeared to be senestopathic and algetic types and agitated depression with depersonalization and derealization.
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