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Soluble TLT-1 modulates platelet-endothelial cell interactions and actin polymerization

Jessica Morales1, Karina Villa, Jim Gattis

  • 1Laboratory of Anatomy and Cell Biology, Universidad Central del Caribe, Bayamón, Puerto Rico.

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|January 23, 2010
PubMed
Summary

Soluble triggering receptor expressed on myeloid cells (TREM)-like transcript-1 (sTLT-1) enhances platelet aggregation and adherence to endothelial cells. Elevated sTLT-1 levels in inflammatory diseases suggest a role in hemostasis.

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