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Updated: Jun 16, 2026

An Ex Vivo Porcine Model for Hydrodynamic Testing of Experimental Aortic Valve Procedures and Novel Medical Devices
Published on: August 25, 2023
Multiple papillary fibroelastomas in rare locations of aortic valve and left ventricular outflow tract: a case report
Masataka Yoda1, Hiroaki Tanabe, Hiroto Kanou
1Department of Cardiovascular Surgery, The Cardiovascular Institute, Tokyo, Japan. myoda@cvi.or.jp
Abstract:
Papillary fibroelastoma (PFE) is the third most common primary neoplasm of the heart. The lesions generally appear singly, but multiple PFEs may rarely occur. The case is reported of multiple PFEs in a woman initially admitted for acute cerebral infarction. Echocardiography revealed four masses, one located on each cusp of the aortic valve and one on the left ventricular outflow tract. All four lesions were successfully removed surgically. An histopathologic examination revealed PFEs arising from the ventricular and valvular endocardium.
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