Related Experiment Video

Updated: Jun 16, 2026

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
09:57

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement

Published on: January 20, 2022

Evaluation of aortic valve stenosis by cardiac multislice computed tomography compared with echocardiography: a

Jawdat Abdulla1, Jacob Sivertsen, Klaus Fuglsang Kofoed

  • 1Division of Cardiology, Department of Medicine, Glostrup University Hospital, Copenhagen, Denmark. jawab@dadlnet.dk

The Journal of Heart Valve Disease
|January 27, 2010
PubMed

Insights

Multi-slice computed tomography (MSCT) reliably quantifies aortic valve area (AVA) in aortic valve stenosis (AVS) patients. This method also accurately assesses coronary anatomy, offering a combined diagnostic approach.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Cardiac Surgery

Background:

  • Aortic valve stenosis (AVS) diagnosis and management require accurate assessment of aortic valve area (AVA).
  • Simultaneous evaluation of coronary anatomy is crucial in AVS patients due to high comorbidity.
  • The diagnostic role of multi-slice computed tomography (MSCT) for both AVA quantification and coronary assessment in AVS remains debated.

Purpose of the Study:

  • To systematically review and meta-analyze the reliability of MSCT for AVA quantification in AVS patients.
  • To evaluate the accuracy of MSCT in assessing coronary anatomy concurrently in AVS patients.

Main Methods:

  • Systematic literature search and meta-analysis of 14 studies involving 470 patients.
  • Comparison of MSCT-derived AVA with transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE).
  • Secondary analysis comparing MSCT accuracy with invasive coronary angiography in 7 studies (266 patients).

Main Results:

  • MSCT planimetry overestimated AVA compared to TTE (bias 0.08 cm², p=0.0001) but showed concordance with TEE (bias -0.02 cm², p=0.71).
  • For detecting significant coronary stenosis versus invasive angiography, MSCT demonstrated 95.5% sensitivity and 81% specificity.
  • Diagnostic odds ratio for MSCT in coronary stenosis detection was 53 (95% CI 19-147).

Conclusions:

  • MSCT is a reliable imaging modality for AVA quantification in patients with AVS.
  • MSCT offers a promising, non-invasive approach for combined assessment of aortic valve morphology and coronary artery disease in AVS patients.
Abstract

More Related Videos

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...