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Updated: Jun 16, 2026

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
Published on: September 20, 2017
[The effect of the composition of hydrophilic base on pharmaceutical availability of prednisolone]
Maria Szcześniak1, Janusz Pluta
1Katedra i Zakład Technologii Postaci Leku, Akademia Medyczna we Wrocławiu. marias@ktpl.am.wroc.pl
Abstract:
Studies on the effect of hydrophilic gel composition on pharmaceutical availability of prednisolone revealed that the half-release times were differentiated depening on the substances added 4% of methylcellulose hydrogel, propylene glycol-1,2 and N,N-dimethylacetamide. Hydrogels containing 15% of N,N-dimethylacetamide and 20% propylene glycol-1,2 as well 0.25% or 0.5% of active substance characterized by the largest pharmaceutical availability, for this gels was found shortened time of prednisolone the half-release.
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