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Updated: Jun 16, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Prostatic carcinoma metastatic to the optic nerve.

Branimir Cerovski¹, Tomislav Vidović, Neda Stiglmayer

¹Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia. bcerov@kbc-zagreb.hr

Collegium Antropologicum

|January 28, 2010

Summary

Prostate cancer rarely metastasizes to the optic nerve, causing vision loss. Early treatment with methylprednisolone can restore vision in these rare cases.

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Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Published on: August 4, 2011

Area of Science:

Ophthalmology
Oncology
Neurology

Background:

Optic nerve infiltration by tumors is more commonly primary than secondary.
Metastases to the optic nerve are rare, with prostatic carcinoma being exceptionally infrequent.

Observation:

A 66-year-old man experienced vision loss due to optic nerve metastasis two years post-prostate surgery.
Initial examination revealed papillary edema and optic nerve functional impairment; later examination showed signs of retrobulbar optic neuropathy.

Findings:

The patient's prostate carcinoma metastasized to the optic nerve, leading to severe vision loss.
Systemic methylprednisolone therapy resulted in significant recovery of visual function.

Implications:

This case highlights the rare occurrence of prostate cancer metastasis to the optic nerve.
Prompt diagnosis and systemic therapy can lead to favorable visual outcomes in such rare presentations.