Related Experiment Video
Updated: Jun 16, 2026

Isolation, Characterization and MicroRNA-based Genetic Modification of Human Dental Follicle Stem Cells
Published on: November 16, 2018
Future approaches in periodontal regeneration: gene therapy, stem cells, and RNA interference
1Department of Developmental Biology, Harvard School of Dental Medicine, 188 Longwood Avenue, REB 513, Boston, MA 02115, USA. giuseppe_intini@hsdm.harvard.edu
Abstract:
Periodontal disease is a major public health issue and the development of effective therapies to treat the disease and regenerate periodontal tissue is an important goal of today's medicine. This article highlights recent scientific advancements in gene therapy, stem cell biology, and RNA interference with the intent of identifying their potential in periodontal tissue regeneration. Results from basic research, preclinical, and clinical studies indicate that these fields of research may soon contribute to more effective regenerative therapies for periodontal disease.
Related Concept Videos
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Microorganisms in Medicine and Therapeutics
Experimental RNAi
Stem Cell Culture
RNA Interference
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...
What is Genetic Engineering?
