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Diffuse fibromuscular dysplasia successfully treated with scoring balloon angioplasty in a 3-year-old boy
Robert F Bonvini1, Aljoscha Rastan, Sebastian Sixt
1Angiology Division, Heart-Center Bad Krozingen, Südring 15, 79189 Bad Krozingen, Germany. robert.bonvini@hcuge.ch
Insights
Fibromuscular dysplasia (FMD) can cause renovascular disease in children. A novel balloon angioplasty technique successfully treated a young boy with severe hypertension and abdominal pain from diffuse FMD.
Area of Science:
- Pediatric Cardiology
- Vascular Biology
- Interventional Radiology
Background:
- Renovascular disease accounts for up to 10% of pediatric arterial hypertension.
- Fibromuscular dysplasia (FMD), a noninflammatory fibroplasia, is a common cause, leading to arterial narrowing.
- Widespread FMD involvement significantly worsens patient outcomes.
Observation:
- A 3.5-year-old boy presented with severe arterial hypertension and abdominal angina.
- The patient exhibited diffuse multivisceral involvement of fibromuscular dysplasia.
- The condition caused significant luminal compromise in multiple arteries.
Findings:
- Successful management of severe pediatric arterial hypertension and abdominal angina was achieved.
- A percutaneous angioplasty approach was employed for treatment.
- A novel balloon catheter was utilized for plaque modulation during the procedure.
Implications:
- This case highlights the potential of percutaneous angioplasty in managing complex pediatric FMD.
- The use of new balloon catheter technology may improve outcomes for diffuse arterial disease.
- Early and effective intervention can mitigate the severe consequences of multivisceral FMD in children.
Abstract:
In children, up to 10% of the cases of arterial hypertension may be caused by a renovascular disease. The etiology of this renovascular disease is most of the time due to a fibromuscular dysplasia (FMD), which causes a noninflammatory intimal-medial fibroplasia leading to luminal compromise. Percutaneous transluminal angioplasty of FMD is a worldwide-accepted treatment modality for this serious arterial disease with, so far, good safety and long-term efficacy data. Once FMD involves several arterial compartments leading to symptoms the outcomes are poor. Herein we report the case of a 3(1/2)-year-old boy with severe arterial hypertension and abdominal angina due to a diffuse multivisceral FMD involvement, successfully managed by a percutaneous angioplasty approach using a new balloon catheter for plaque modulation.
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