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Published on: September 11, 2015
Light-curable polymer/calcium phosphate nanocomposite glue for bone defect treatment
Oliver D Schneider1, Alexander Stepuk, Dirk Mohn
1Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.
Acta Biomaterialia
|January 30, 2010
Summary
This study developed a light-curable dental resin composite with amorphous calcium phosphate nanoparticles. This innovative material significantly enhances adhesion to wet bone, offering new possibilities for bone repair and dental implants.
Area of Science:
- Biomaterials Science
- Dental Materials
- Nanotechnology
Background:
- Methacrylate-based resins are used in dentistry for defect repair.
- Current limitations exist in applying these resins to wet biological tissues like bone.
Purpose of the Study:
- To investigate the application of light-curable polymers for bonding wet bone.
- To enhance the adhesion properties of dental resins for broader applications.
Main Methods:
- A composite was developed using methacrylate-based resin and amorphous calcium phosphate nanoparticles (a-CaP).
- Adhesion to wet cow hip bone was tested in a near in vivo setup.
- In vitro bioactivity, compressive, and tensile strength tests were performed.
Main Results:
- The composite demonstrated significantly improved adhesion to wet bone surfaces.
- The amorphous CaP filler recrystallized to hydroxyapatite within minutes, enhancing bonding.
- The material showed promising results in bioactivity and mechanical strength tests.
Conclusions:
- Light-curable nanocomposites with reactive fillers show potential for improved wet bone adhesion.
- These materials could be suitable for complex-shaped, load-bearing implant materials and fracture repair.
