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Updated: Jun 16, 2026

Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles
Published on: July 5, 2016
Detection of metallic elements from paraffin-embedded tissue blocks by energy dispersive X-ray fluorescence
Motonori Takahashi1, Hiroshi Kinoshita, Minori Nishiguchi
1Department of Legal Medicine, Hyogo College of Medicine, Hyogo 663-8501, Japan. gengring@hyo-med.ac.jp
Abstract:
Energy dispersive X-ray fluorescence spectrometry (EDX) enables rapid, non-destructive, multi-elemental analysis. Using EDX, lead and some other metallic elements were detected in paraffin-blocks in which skin samples from a gunshot wound were embedded. Lead was not identified in control samples from non-injured cases. These findings indicate that EDX is a useful method for rapid non-destructive analysis of paraffin-embedded blocks. This technique can provide scientific evidence for identification of a firearm even after storing the sample for a long time.
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