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Updated: Jun 16, 2026

An In Ovo Model for Testing Insulin-mimetic Compounds
Published on: April 23, 2018
[Studies on the lowering blood sugar substances from agrimony]
Jian-Hong Zhang1, You-Sheng Chen
1Department of Pharmacy, Guangdong Food and Drug Vocational College, Guangzhou 510520, China. zhangjh@gdyzy.edu.cn
Objective:
To isolate and identify the chemical constituents from the active section lowering blood sugar of agrimony.
Methods:
The compounds were separated by repeated silica gel, Sephadex LH-20 and HPLC chromatographies. The structures of compounds isolated were identified by analysis of their spectral data and chemical properties.
Results:
Nine compounds were isolated from the active section with lowering blood sugar of agrimony and their structures were identified as apigenin-7-O-3-D-glucopyranoside (1), catechin (2), quercetin (3), rutin (4), kaempferol-3-O-alpha-L-rhamnoside (5), Kampferol-3-O-beta-D-glucopyranoside (6), lutcolin-7-O-beta-D-glucopyranosidc (7), 19alpha, 24-dihydroxy ursolic acid (8), 3,3'-di-O-mcthyl ellagic acid4-O-beta-D-glucopyranoside (9).
Conclusion:
Compounds 1, 7, 8, 9 are isolated from thia plant for the first time.
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